Which of the following statement is not correct?
Crick postulated the presence of adapter molecule
Amino acids have structural specialties to read the genetic code uniquely
Polynucleotide phosphorylase is helpful in RNA synthesis in template-independent manner
If two charged tRNAs are brought close enough, the formation of peptide bond takes place between them
Solution
Option (1) Francis Crick First postulated the presence of an adapter molecule that would on one hand read the code and on other hand would bind to specific amino acids.
Option (2) Amino acids have structural specialties to read the genetic code uniquely
This is incorrect as, tRNA brings Amino acids and reads the genetic code.
Option (3) Polynucleotide phosphorylase polymerizes RNA with defined sequence in a template independent manner. PNPase is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity.
Option (4) Aminoacylation of tRNA or charging of tRNA is the activation of amino acids in the presence of ATP and their linkage to their eognate tRNA. If two such charged tRNAs are brought close enough, the formation of peptide bond between them would be favoured energetically.
Hence, Option (2) statement is not correct. Therefore, option (2) is correct answer.
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